A statistical procedure to map high-order epistasis for complex traits
نویسندگان
چکیده
منابع مشابه
A statistical procedure to map high-order epistasis for complex traits
Genetic interactions or epistasis have been thought to play a pivotal role in shaping the formation, development and evolution of life. Previous work focused on lower-order interactions between a pair of genes, but it is obviously inadequate to explain a complex network of genetic interactions and pathways. We review and assess a statistical model for characterizing high-order epistasis among m...
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ژورنال
عنوان ژورنال: Briefings in Bioinformatics
سال: 2012
ISSN: 1467-5463,1477-4054
DOI: 10.1093/bib/bbs027